University Hospital of Ludwig Maximilian University – latest trends in the cancer immunotherapy
According to the data of the Times Higher Education World University Ranking, the Ludwig Maximilian University of Munich takes the leading position in the field of “Clinical, pre-clinical and health” issues. Therefore, it is not surprising that doctors from the University Hospital of LMU offer patients promising results of the latest clinical research in oncology, cardiology, and neurology.
According to the data of the Times Higher Education World University Ranking, the Ludwig Maximilian University of Munich takes the leading position in the field of “Clinical, pre-clinical and health” issues. Therefore, it is not surprising that doctors from the University Hospital of LMU offer patients promising results of the latest clinical research in oncology, cardiology, and neurology. In 2019, Prof. Dr. Sebastian Kobold and his medical team have received the m4 Award for the development of CARMOUFLAGE, which is an innovative platform for the T-cell therapy performing.
Cutting edge technologies in Gene Center Munich
Gene Center Munich is one of the University Hospital of LMU departments. Its clinical focuses include investigating cancer immunology which is helpful in selecting the most suitable and individual immunotherapy for each patient. In addition to high selectivity and good tolerance, immunotherapy allows fighting the refractory cancer cells.
Specialists conduct researches in several areas of clinical oncology. These are identification of the target tumor antigens and other possible target structures, passive immunotherapy with antibodies, bispecific antibody constructs with T-cells, vaccines with autologous dendritic cells, exploring the prognostic, diagnostic and predictive biomarkers, etc.
“Re-educating” T-cells for tumor recognition and fighting is the promising approach in cancer treatment. The technique is efficient in a variety of solid and hematological malignancies. T-cells are used in the native form, in combination with antibodies and in the modified form, i.e. CAR T-cells.
CARMOUFLAGE for CAR T-cell therapy – 500.000 EUR for the research
Working out the idea of T-cells application, Prof. Dr. Sebastian Kobold with his medical team from the Division of Clinical Pharmacology has created the CARMOUFLAGE platform. The platform allows the direct access of CAR T-cells to tumor tissue without any traumatic surgery. This enhances impact of the CAR T-cells on solid tumors that is typically restricted due to the tumor-associated immunosuppression and inadequate access of T-cells to malignant cells. One more positive effect of the platform is enhancement the of CAR T-cells cytotoxic activity.
To date, the CAR T-cell therapy is used in the treatment of certain leukemias and lymphomas. The research project will be funded with around 500,000 euros for the further development. The therapeutic safety of the approach should be proven along with possibility of wide clinical using in the specialized medical facilities.
Treatment in the University Hospital of LMU with Booking Health
University Hospital of Ludwig Maximilian University of Munich provides high-quality medical services to citizens of Germany and international patients. People, who come here from abroad, need to take care of a numerous administrative issues. Those ones who want to save time and money may delegate organization of treatment to Booking Health.
Booking Health is the international provider of medical tourism that offers help in:
- Establishing communication with the hospital and booking the appointment.
- Preparing and discussing the preliminary medical program.
- Monitoring medical program implementation, arrangement of additional tests and procedures.
- Help in buying and forwarding medicines.
- Providing favorable cost of treatment, without overpricing and additional fees for foreign patients (saving up to 50%).
- Communication with the clinic after medical program completion, receiving medical reports and translating them into your native language.
- Control of the final calculation and return of unspent funds.
- Arranging the trip itself: booking hotels and plane tickets, services of interpreter, transfer organization.